Short answer: choose OpenAI Agents SDK when you want a lightweight, OpenAI-native way to build agents with tools, handoffs, guardrails, sessions, and tracing. Choose LangGraph when your workflow needs durable state, explicit control flow, branching, retries, human review, and complex multi-step orchestration.
For many production systems, the best answer is not one or the other. A team can use LangGraph as the orchestration layer and use OpenAI Agents SDK inside specific nodes or tasks where OpenAI-native agent execution is the right fit.
At V12 Labs, we think about this less as a framework debate and more as a workflow architecture decision: what needs to be automated, where state must live, where humans need control, and what happens when the model is wrong.
